NASDAQ : HRTX
$0.0 (0.75%)
1.54%
25
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0.00
change: -189.8772 | last: 1.89881.54M
| Filing Date | Reporting Person | Amount Beneficially Owned | % of Class |
|---|---|---|---|
| 2026-05-13 | Adage Capital Management, L.P. | - | 0.00% |
| 2026-03-27 | The Vanguard Group | - | 0.00% |
| 2026-02-17 | Clearline Capital LP | 12.24M | 6.70% |
| 2026-01-30 | The Vanguard Group | 9.82M | 5.35% |
| 2025-11-26 | Clearline Capital LP | 9.71M | 5.30% |
| 2025-10-30 | The Vanguard Group | 8.46M | 4.61% |
| 2025-10-17 | Rubric Capital Management LP | 30.05M | 15.90% |
| 2025-10-17 | David Rosen | 30.05M | 15.90% |
| 2025-08-12 | David Rosen | 29.1M | 17.50% |
| 2025-08-12 | Rubric Capital Management LP | 29.1M | 17.50% |
| 2024-11-12 | Adage Capital Management, L.P. | 8.85M | 5.84% |
| 2024-11-12 | Robert Atchinson | 8.85M | 5.84% |
| 2024-11-12 | Phillip Gross | 8.85M | 5.84% |
| 2024-10-24 | (1) BlackRock, Inc. | 8.53M | 5.60% |
| 2023-04-13 | Dr. Jeffrey R. Jay, M.D. | 6.36M | 5.35% |
| 2023-04-13 | Great Point Partners, LLC | 6.36M | 5.35% |
| 2023-04-13 | Mr. Ortav Yehudai | 6.36M | 5.35% |
| 2023-02-06 | Rubric Capital Management LP | 11.75M | 9.90% |
| 2023-02-06 | Velan Capital Investment Management LP | 4.5M | 3.80% |
| 2023-02-06 | Velan Capital Master Fund LP | 4.5M | 3.80% |
| 2023-02-06 | Velan Capital Holdings LLC | 4.5M | 3.80% |
| 2023-02-06 | David Rosen | 11.75M | 9.90% |
| 2023-02-06 | Velan Capital Management LLC | 4.5M | 3.80% |
| 2023-02-06 | Balaji Venkataraman | 4.5M | 3.80% |
| 2023-02-06 | Adam Morgan | 4.5M | 3.80% |
| 2022-08-19 | Deep Track Biotechnology Master Fund, Ltd. | 12.23M | 9.99% |
| 2022-08-19 | David Kroin | 12.23M | 9.99% |
| 2022-08-19 | Deep Track Capital, LP | 12.23M | 9.99% |
| 2022-04-11 | SSGA FUNDS MANAGEMENT, INC. | 11.04M | 10.81% |
| 2022-04-11 | STATE STREET CORPORATION | 12.92M | 12.65% |
| 2022-02-14 | Baker Bros. Advisors LP | 8.13M | 8.00% |
| 2022-02-14 | ArrowMark Colorado Holdings, LLC | 6.41M | 6.28% |
| 2022-02-14 | UBS O’Connor LLC | 8.28M | 8.12% |
| 2022-02-11 | STATE STREET CORPORATION | 7.69M | 7.55% |
| 2022-02-11 | SSGA FUNDS MANAGEMENT, INC. | 5.96M | 5.85% |
| 2022-02-10 | The Vanguard Group - 23-1945930 | 9.61M | 9.43% |
| 2022-02-04 | Wellington Investment Advisors Holdings LLP | 1.64M | 1.61% |
| 2022-02-04 | Wellington Management Group LLP | 1.64M | 1.61% |
| 2022-02-04 | Wellington Group Holdings LLP | 1.64M | 1.61% |
| 2022-02-03 | Pershing Square Capital Management, L.P. | - | 0.00% |
| 2022-02-01 | (1) BlackRock, Inc. | 7.68M | 7.50% |
| 2022-01-24 | JPMORGAN CHASE & CO.13-2624428 | 6.25M | 6.10% |
| 2021-02-16 | Felix J. Baker | 8.06M | 8.70% |
| 2021-02-16 | Baker Bros. Advisors LP | 8.06M | 8.70% |
| 2021-02-16 | ArrowMark Colorado Holdings, LLC | 5.36M | 5.90% |
| 2021-02-16 | Julian C. Baker | 8.06M | 8.70% |
| 2021-02-16 | Baker Bros. Advisors (GP) LLC | 8.06M | 8.70% |
| 2021-02-11 | EIN #00-0000000 | - | 0.00% |
| 2021-02-10 | The Vanguard Group - 23-1945930 | 8.31M | 9.15% |
| 2021-02-04 | Wellington Management Company LLP | 5.97M | 6.57% |
| 2021-02-04 | Wellington Management Group LLP | 6.94M | 7.63% |
| 2021-02-04 | Wellington Group Holdings LLP | 6.94M | 7.63% |
| 2021-02-04 | Wellington Investment Advisors Holdings LLP | 6.94M | 7.63% |
| 2021-01-29 | (1) BlackRock, Inc. | 6.89M | 7.60% |
| 2020-02-14 | Julian C. Baker | 7.98M | 8.70% |
| 2020-02-14 | Baker Bros. Advisors LP | 7.98M | 8.70% |
| 2020-02-14 | Baker Bros. Advisors (GP) LLC | 7.98M | 8.70% |
| 2020-02-14 | Felix J. Baker | 7.98M | 8.70% |
| 2020-02-13 | Board of Directors of MetLife, Inc., as an entity | 172.03M | 15.50% |
| 2020-02-12 | The Vanguard Group - 23-1945930 | 7.86M | 8.72% |
| 2020-02-07 | Abigail P. Johnson | 6.58M | 7.31% |
| 2020-02-07 | FMR LLC | 6.58M | 7.31% |
| 2020-02-05 | (1) BlackRock, Inc. | 5.77M | 6.40% |
| 2020-01-08 | Wellington Management Group LLP | 4.59M | 5.10% |
| 2020-01-08 | Wellington Group Holdings LLP | 4.59M | 5.10% |
| 2020-01-08 | Wellington Investment Advisors Holdings LLP | 4.59M | 5.10% |
| 2019-02-13 | Baker Bros. Advisors (GP) LLC | 6.91M | 8.60% |
| 2019-02-13 | Baker Bros. Advisors LP | 6.91M | 8.60% |
| 2019-02-13 | Julian C. Baker | 6.91M | 8.60% |
| 2019-02-13 | Felix J. Baker | 6.91M | 8.60% |
| 2019-02-12 | Wellington Management Company LLP | 3.96M | 5.08% |
| 2019-02-12 | Wellington Investment Advisors Holdings LLP | 4.58M | 5.87% |
| 2019-02-12 | Wellington Group Holdings LLP | 4.58M | 5.87% |
| 2019-02-12 | Wellington Management Group LLP | 4.58M | 5.87% |
| 2019-02-08 | (1) BlackRock, Inc. | 4.91M | 6.30% |
| 2018-08-10 | Wilks Brothers, LLC | 3.61M | 12.40% |
| 2018-02-13 | Felix J. Baker | 4.85M | 7.30% |
| 2018-02-13 | Baker Bros. Advisors LP | 4.85M | 7.30% |
| 2018-02-13 | Baker Bros. Advisors (GP) LLC | 4.85M | 7.30% |
| 2018-02-13 | FMR LLC | 9.63M | 15.00% |
| 2018-02-13 | Abigail P. Johnson | 9.63M | 15.00% |
| 2018-02-13 | Julian C. Baker | 4.85M | 7.30% |
| 2017-06-12 | Portugal Telecom, SGPS, S.A. | 137.27M | 49.43% |
| 2017-02-08 | Brian A. Selmo | 3.69M | 12.60% |
| 2017-02-08 | (1) BlackRock, Inc. | 2.33M | 4.50% |
| 2017-02-01 | 98-0557567 | 585.82K | 1.50% |
| 2017-01-30 | (1) BlackRock, Inc. | 2.01M | 5.50% |
| 2016-05-10 | Vornado Realty Trust | 7.94M | 33.60% |
| 2016-02-16 | Bihua Chen | 1.69M | 4.70% |
| 2016-02-16 | Cormorant Global Healthcare GP, LLC | 1.69M | 4.70% |
| 2016-02-16 | Cormorant Asset Management, LLC | 1.69M | 4.70% |
| 2016-02-16 | Baker Bros. Advisors LP | 3.67M | 10.00% |
| 2016-02-16 | Cormorant Global Healthcare Master Fund, LP | 1.69M | 4.70% |
| 2016-02-16 | Julian C. Baker | 3.67M | 10.00% |
| 2016-02-16 | Felix J. Baker | 3.67M | 10.00% |
| 2016-02-16 | Baker Bros. Advisors (GP) LLC | 3.67M | 10.00% |
| 2016-02-12 | Abigail P. Johnson | 5.4M | 15.00% |
| 2016-02-12 | FMR LLC | 5.4M | 15.00% |
| 2016-02-10 | 98-0557567 | 3.31M | 9.20% |
| 2016-02-05 | President and Fellows of Harvard College | 337.6K | 5.60% |
| 2016-02-05 | President and Fellows of Harvard College | 383.7K | 6.40% |
| 2016-01-28 | Savitr Capital, LLC | 772K | 2.10% |
| 2016-01-28 | Standard Pacific Capital Holdings, LLC | 772K | 2.10% |
| 2016-01-28 | Savitr Capital, LLC | 1.79M | 6.10% |
| 2016-01-28 | Savitr Capital, LLC | 772K | 2.10% |
| 2016-01-28 | Moses Trust | 15000.0 | 0.00% |
| 2016-01-28 | Savitr Peak Energy Fund II LP | 1.71M | 5.90% |
| 2016-01-28 | Moses Trust | 79238.0 | 0.30% |
| 2016-01-28 | Andrew R. Midler | 1.79M | 6.10% |
| 2016-01-28 | Savitr Peak Energy Fund II LP | 757K | 2.10% |
| 2016-01-28 | Moses Trust | 15000.0 | 0.00% |
| 2016-01-28 | Andrew R. Midler | 772K | 2.10% |
| 2016-01-28 | Andrew R. Midler | 772K | 2.10% |
| 2015-08-28 | Cormorant Global Healthcare GP, LLC | 1.99M | 5.60% |
| 2015-08-28 | Bihua Chen | 1.99M | 5.60% |
| 2015-08-28 | Cormorant Asset Management, LLC | 1.99M | 5.60% |
| 2015-08-28 | Cormorant Global Healthcare Master Fund, LP | 1.99M | 5.60% |
| 2015-06-08 | Kingdon Capital Management, L.L.C. | 2.83M | 9.56% |
| 2015-06-08 | M. Kingdon Offshore Master Fund L.P. | 1.56M | 5.27% |
| 2015-06-08 | Mark Kingdon | 2.83M | 9.56% |
| 2015-02-13 | Moses Trust | 79238.0 | 0.30% |
| 2015-02-13 | Standard Pacific Capital Holdings, LLC | 1.79M | 6.10% |
| 2015-02-13 | Savitr Capital, LLC | 1.79M | 6.10% |
| 2015-02-13 | Andrew R. Midler | 1.79M | 6.10% |
| 2014-02-14 | Felix J. Baker | 46.36M | 9.99% |
| 2014-02-14 | Daniel R. Omstead | 20.6M | 4.20% |
| 2014-02-14 | Tekla Capital Management LLC | 20.6M | 4.20% |
| 2014-02-14 | BVF Partners L.P. | 2.88M | 1.00% |
| 2014-02-14 | Biotechnology Value Fund, L.P. | 1.46M | 1.00% |
| 2014-02-14 | Julian C. Baker | 46.36M | 9.99% |
| 2014-02-14 | Biotechnology Value Fund II, L.P. | 984.5K | 1.00% |
| 2014-02-14 | BVF Investments, L.L.C. | - | 0.00% |
| 2014-02-14 | 13-4093645 | 46.36M | 9.99% |
| 2014-02-14 | BVF Inc. | 2.88M | 1.00% |
| 2014-02-14 | 46-3147749 | 46.36M | 9.99% |
| 2014-02-14 | Investment 10, L.L.C. | 434.8K | 1.00% |
| 2014-02-14 | Mark N. Lampert | 2.88M | 1.00% |
| 2014-02-10 | NS Advisors, LLC | 580.73K | 6.60% |
| 2013-06-10 | FMR LLC | - | 0.00% |
| 2013-06-10 | Edward C. Johnson 3d | - | 0.00% |
| 2013-04-12 | Andrew R. Midler | 38.1M | 12.60% |
| 2013-04-12 | Standard Pacific Capital Holdings, LLLP | 38.1M | 12.60% |
| 2013-04-12 | Savitr Capital, LLC | 38.1M | 12.60% |
| 2013-04-12 | The Moses Trust | 1.9M | 0.60% |
| 2013-02-15 | 66-0705618 | 38.1M | 11.80% |
| 2013-02-14 | FMR LLC | 15.24M | 5.04% |
| 2013-02-14 | Edward C. Johnson 3d | 15.24M | 5.04% |
| 2013-02-12 | Energy Transfer Equity, L.P. | 39.06M | 95.93% |
| 2012-12-31 | Kevin Kotler | 15.52M | 5.14% |
| 2012-12-31 | Broadfin Healthcare Master Fund, Ltd. | 15.52M | 5.14% |
| 2012-12-31 | Broadfin Capital, LLC | 15.52M | 5.14% |
| 2012-09-27 | Standard Pacific Capital Holdings, LLLP | 36.19M | 11.80% |
| 2012-09-27 | The Moses Trust | 1.9M | 0.60% |
| 2012-09-27 | Andrew R. Midler | 38.1M | 12.60% |
| 2012-02-10 | BVF Inc. | 19.95M | 9.70% |
| 2012-02-10 | Investment 10, L.L.C. | 1.3M | 1.00% |
| 2012-02-10 | BVF Partners L.P. | 19.95M | 9.70% |
| 2012-02-10 | Biotechnology Value Fund, L.P. | 4.37M | 2.20% |
| 2012-02-10 | BVF Investments, L.L.C. | 11.36M | 5.60% |
| 2012-02-10 | Biotechnology Value Fund II, L.P. | 2.92M | 1.50% |
| 2012-02-10 | Mark N. Lampert | 19.95M | 9.70% |
| 2011-09-12 | Franklin Resources, Inc. | 22.29M | 10.70% |
| 2011-07-08 | BVF Partners L.P. | 20M | 9.70% |
| 2011-07-08 | Biotechnology Value Fund, L.P. | 4.38M | 2.20% |
| 2011-07-08 | Biotechnology Value Fund II, L.P. | 2.95M | 1.50% |
| 2011-07-08 | BVF Inc. | 20M | 9.70% |
| 2011-07-08 | Mark N. Lampert | 20M | 9.70% |
| 2011-07-08 | BVF Investments, L.L.C. | 11.36M | 5.60% |
| 2011-07-08 | Investment 10, L.L.C. | 1.3M | 1.00% |
| 2011-07-07 | Tang Capital Partners, LP | 60.44M | 30.20% |
| 2011-07-07 | Tang Capital Management, LLC | 60.44M | 30.20% |
| 2011-07-07 | Kevin C. Tang | 61.22M | 30.60% |
| 2011-07-07 | Felix J. Baker | 20.53M | 9.99% |
| 2011-07-07 | Julian C. Baker | 20.53M | 9.99% |
| 2011-05-03 | Julian C. Baker | 6.86M | 17.13% |
| 2011-05-03 | Felix J. Baker | 6.86M | 17.13% |
| 2011-02-03 | Deerfield Capital, L.P. | 92557.0 | 0.23% |
| 2011-02-03 | Deerfield Special Situations Fund International Limited | 163.12K | 0.41% |
| 2011-02-03 | James E. Flynn | 255.68K | 0.63% |
| 2011-02-03 | Deerfield Management Company, L.P. | 163.12K | 0.41% |
| 2011-02-03 | Deerfield Special Situations Fund, L.P. | 92557.0 | 0.23% |
| 2009-10-29 | C. Baker | 9.44M | 22.53% |
| 2009-10-29 | Felix J. Baker | 9.44M | 22.53% |
| 2009-02-17 | Felix J. Baker | 2.88M | 9.30% |
| 2009-02-17 | Julian C. Baker | 2.88M | 9.30% |
| 2009-02-13 | Visium Asset Management, LP | - | 0.00% |
| 2009-02-13 | Jacob Gottlieb | - | 0.00% |
| 2008-08-15 | J. Baker | 2.26M | 7.30% |
| 2008-08-15 | C. Baker | 2.26M | 7.30% |
| 2008-02-14 | C. TANG | 4.61M | 15.00% |
| 2008-02-14 | CAPITAL MANAGEMENT, LLC | 4M | 13.00% |
| 2008-02-14 | Deerfield Capital, L.P. | 841.45K | 2.73% |
| 2008-02-14 | Deerfield Special Situations Fund International Limited | 1.54M | 5.00% |
| 2008-02-14 | Deerfield Management Company, L.P. | 1.54M | 5.00% |
| 2008-02-14 | Deerfield Special Situations Fund, L.P. | 841.45K | 2.73% |
| 2008-02-14 | CAPITAL PARTNERS, LP | 4M | 13.00% |
| 2008-02-14 | James E. Flynn | 2.38M | 7.74% |
| 2007-06-20 | RA Capital Management, LLC | 2.42M | 8.80% |
| 2007-06-20 | RA Capital Biotech Fund, L.P. | 2.38M | 8.60% |
| 2007-06-20 | Peter Kolchinsky | 2.42M | 8.80% |
| 2007-06-20 | Richard H. Aldrich | 2.42M | 8.80% |
| 2007-06-19 | Deerfield Capital, L.P. | 834.56K | 3.03% |
| 2007-06-19 | Deerfield Special Situations Fund, L.P. | 834.56K | 3.03% |
| 2007-06-19 | Deerfield Management Company, L.P. | 1.45M | 5.26% |
| 2007-06-19 | James E. Flynn | 2.28M | 8.28% |
| 2007-06-19 | Deerfield Special Situations Fund International Limited | 1.45M | 5.26% |
| 2006-09-08 | North Sound Capital LLC (1) | 1M | 3.90% |
| 2006-03-10 | #39-1078128 | 1.08M | 4.30% |
| 2006-03-10 | WILLIAM J. NASGOVITZ | 1.08M | 4.30% |
| 2006-02-14 | North Sound Capital LLC (1) | 2.33M | 9.20% |
| 2006-02-03 | #39-1078128 | 1.43M | 5.70% |
| 2006-02-03 | WILLIAM J. NASGOVITZ | 1.43M | 5.70% |
| 2006-01-10 | 04-2683227 | 745.4K | 2.95% |
| 2005-01-28 | North Sound Capital LLC (1) | 2.36M | 9.44% |
| 2005-01-13 | WILLIAM J. NASGOVITZ | 1.56M | 6.22% |
| 2005-01-13 | #39-1078128 | 1.56M | 6.22% |
| 2004-05-04 | North Sound Capital LLC (1) | 1.07M | 5.20% |
| 2004-02-12 | WILLIAM J. NASGOVITZ | 1.32M | 6.40% |
| 2004-02-12 | #39-1078128 | 1.32M | 6.40% |
| 2003-02-12 | 04-2683227 | 1.62M | 7.92% |
| 2002-02-12 | 04-2683227 | 1.62M | 7.99% |
| 2001-02-14 | 22-1024240 | - | 0.00% |
| 2001-02-14 | 22-2007137 | - | 0.00% |
| 2001-02-12 | 04-2683227 | 1.62M | 8.03% |
| 1996-02-05 | GDK, Inc. | 617.72K | 3.60% |
| 1996-02-05 | 13-3512778 | - | 0.00% |
| Date | Stock Price | Shares Outstanding | Market Cap | Cash & Equivalents | Total Debt | Enterprise Value |
|---|---|---|---|---|---|---|
| 2025-12-31 | $1.30 | 166.71M | $216.72M | $28.65M | $140.64M | $328.71M |
| 2024-12-31 | $1.53 | 152.45M | $233.25M | $25.8M | $177.76M | $385.21M |
| 2023-12-31 | $1.70 | 138.14M | $234.83M | $28.68M | $179.63M | $385.78M |
| 2022-12-31 | $2.50 | 109M | $272.49M | $15.36M | $157.48M | $414.6M |
| 2021-12-31 | $9.13 | 98.47M | $899.04M | $90.54M | $159.5M | $967.99M |
| 2020-12-31 | $21.17 | 90.77M | $1.92B | $105.14M | $24.61M | $1.84B |
| 2019-12-31 | $23.50 | 81.78M | $1.92B | $71.9M | $19.79M | $1.87B |
| 2018-12-31 | $25.94 | 73.19M | $1.9B | $31.84M | $4.57M | $1.87B |
| 2017-12-31 | $18.10 | 54.04M | $978.12M | $144.58M | $28.68M | $862.22M |
| 2016-12-31 | $13.10 | 37.92M | $496.82M | $13.41M | $52.91M | $536.31M |
| Date | Stock Price | Shares Outstanding | Market Cap | Cash & Equivalents | Total Debt | Enterprise Value |
|---|---|---|---|---|---|---|
| 2026-03-31 | $0.80 | 189.65M | $151.74M | $26.12M | $141.63M | $267.25M |
| 2025-12-31 | $1.30 | 166.71M | $216.72M | $28.65M | $140.64M | $328.71M |
| 2025-09-30 | $1.26 | 170.35M | $214.64M | $43.07M | $140.44M | $312.01M |
| 2025-06-30 | $2.07 | 154.02M | $318.82M | $16.52M | $176.74M | $479.05M |
| 2025-03-31 | $2.20 | 153.49M | $337.68M | $19.27M | $177.26M | $495.66M |
| 2024-12-31 | $1.53 | 153.15M | $234.32M | $25.8M | $177.76M | $386.28M |
| 2024-09-30 | $1.99 | 152.83M | $304.13M | $25.74M | $178.25M | $456.64M |
| 2024-06-30 | $3.47 | 152.3M | $528.5M | $18.39M | $178.71M | $688.82M |
| 2024-03-31 | $2.71 | 151.2M | $409.75M | $20.45M | $179.17M | $568.47M |
| 2023-12-31 | $1.70 | 150.28M | $255.48M | $28.68M | $179.63M | $406.44M |
| 2023-09-30 | $1.03 | 144.99M | $149.34M | $34.86M | $180M | $294.48M |
| 2023-06-30 | $1.16 | 119.72M | $138.87M | $13.46M | $156.12M | $281.54M |